A reference manager can be a very useful tool when you are doing a literature review. It helps you to organize your references in a systematic way.
With a reference manager, like Zotero, you can do many things
Export references from a bibliographic database to your reference manager, including, when available, the abstract and keywords used in the item record. The reference manager displays bibliographical data from different databases in a uniform format - this makes it easier to scan the titles and abstracts to decide which articles you want to read.
Each database has its own procedure for exporting references into a reference manager.
Create folders to categorize your references. How you describe the folders is up to you, you can create folders per database, per topic, per 'status of the document' (to read, read, useful, not relevant), etc.
Use additional fields, to add your own keywords and remarks.
Use the deduplicate option for where you have lots of duplicated items returned from your different searches.
Use the link resolver to find the full text of an article.
Store the full text PDFs for the article citations in your reference manager.
MIT supports and recommends the use of the reference manager Zotero. Zotero is a free and easy to use Reference Manager, with a lot of functionality, and is commonly used in many Universities. For assistance with using Zotero, see the MIT Using Zotero Guide or speak to your Campus Librarian